Rabbit Secondary Antibodies
ABclonal Technology 594 Rabbit anti-Human CDA
This gene encodes an enzyme involved in pyrimidine salvaging The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine respectively It is one of several deaminases responsible for maintaining the cellular pyrimidine pool Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias
ABclonal Technology 700 Rabbit anti-Human CD2
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 flanking sequence of this gene
ABclonal Technology 700 Rabbit anti-Human CD2
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 flanking sequence of this gene
ABclonal Technology 594 Rabbit anti-Human EGFR
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily This protein is a receptor for members of the epidermal growth factor family EGFR is a cell surface protein that binds to epidermal growth factor Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation Mutations in this gene are associated with lung cancer
Sino Biological Rabbit Anti-Human IgG3 Secondary Antibody, Rabbit MAb 100µL
Rabbit Anti-Human IgG3 Secondary Antibody, Rabbit MAb 100µL
ABclonal Technology 405 Rabbit anti-Human IgD
IgD is the major antigen receptor isotype on the surface of most peripheral B-cells where it is coexpressed with IgM The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases
ABclonal Technology 647 Rabbit anti-Human CEACAM6
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma This gene affects the sensitivity of tumor cells to adenovirus infection The protein encoded by this gene acts as a receptor for adherent-invasive E coli adhesion to the surface of ileal epithelial cells in patients with Crohn s disease This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19
ABclonal Technology 488 Rabbit anti-Human TLR1
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity TLRs are highly conserved from Drosophila to humans and share structural and functional similarities They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity The various TLRs exhibit different patterns of expression This gene is ubiquitously expressed and at higher levels than other TLR genes Different length transcripts presumably resulting from use of alternative polyadenylation site and or from alternative splicing have been noted for this gene
ABclonal Technology PE Rabbit anti-Human GPRC5D
The protein encoded by this gene is a member of the G protein-coupled receptor family however the specific function of this gene has not yet been determined
ABclonal Technology 488 Rabbit anti-Human GPRC5D
The protein encoded by this gene is a member of the G protein-coupled receptor family however the specific function of this gene has not yet been determined
ABclonal Technology 594 Rabbit anti-Human CD131
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3 IL-5 and CSF Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)
ABclonal Technology 488 Rabbit anti-Human AXL
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal followed by two fibronectin type-III motifs It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) This gene may be involved in several cellular functions including growth migration aggregation and anti-inflammation in multiple cell types The encoded protein acts as a host cell receptor for multiple viruses including Marburg Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus
ABclonal Technology 450 Rabbit anti-Human CD138
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family The syndecans mediate cell binding cell signaling and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins Altered syndecan-1 expression has been detected in several different tumor types While several transcript variants may exist for this gene the full-length natures of only two have been described to date These two represent the major variants of this gene and encode the same protein
ABclonal Technology 647 Rabbit anti-Human CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is expressed by activated but not by resting T and B cells TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported